By Jacqueline Jumpsen
'This book's target is to supply a centred assessment (morphological, biochemical and practical) of mind improvement and to exemplify the function of lipids within the very important developmental occasions and the recommendations which are most likely altered by way of physiological alterations in mind lipid composition. person chapters contain: mind progress and vulnerability; mind lipids; Lipids and crucial fatty acids in mind improvement; crucial fatty acid synthesis and delivery to the mind; influence of nutrition on fatty acid composition in mind; Glycolipids and gangliosides; Neurotransmitters; and Relevance, reflections and destiny directions.'
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Extra info for Brain development : relationship to dietary lipid and lipid metabolism
The distribution to and utilization by various organs of dietary fatty acids depends, in part, on their structure. The tendency exists for medium-chain-length fatty acids to be used for energy, whereas the longer-chain saturated and monounsaturated fatty acids tend to be used for storage. This process may occur indirectly, via the liver, or directly. The liver possesses two well-defined systems for the active chain elongation of fatty acids: the mitochondrial system and the endoplasmic reticulum system.
The degree of resolution is preserved in the retina as well as in the lateral geniculate nucleus and the visual cortex. Thus, visual acuity is associated primarily with retinal function, but also indicates some measure of function of other areas in the visual system. Essential Fatty Acids and the Retina As cellular differentiation and active synaptogenesis occur, photoreceptor biosynthesis is also taking place. In photoreceptor outer segments (rod outer segments), the level of 22:6n-3 can account for up to 50% of all fatty acids, depending on the phospholipid class (Fliesler and Anderson, 1983).
Leukotrienes are produced via the lipoxygenase pathway (Leaf and Copyright © 1995 AOCS Press Weber, 1988) (Fig. 3) and play a role in constriction of bronchial airway musculature, in vascular permeability, and in interactions between the endothelium and white cell population. These conjugated trienes are formed in response to immunologic and nonimmunologic stimuli (Mayes, 1993). Insertion of oxygen into the 5, 12, and 15 positions of arachidonic acid by three different lipoxygenases gives rise to hydroperoxides (HPETEs).
Brain development : relationship to dietary lipid and lipid metabolism by Jacqueline Jumpsen